Archives: articles

Devanssh MehtaM.Pharm. (Pharmacology), MBA, B.Pharm.Independent Pharmaceutical Author and Research ScholarMeerut, Uttar Pradesh, India Abstract Metronidazole represents one of the most significant antimicrobial discoveries of the twentieth century, particularly in the treatment of anaerobic bacterial and protozoal infections. Since its introduction in the 1950s, this nitroimidazole derivative has become an indispensable component of modern anti-infective pharmacotherapy. Its unique mechanism of action,…

Author: Devanssh MehtaM.Pharm (Pharmacology), MBA, B.PharmPharmaceutical Author and Research Scholar, Meerut, India Abstract The emergence of biologic medicines has revolutionized modern therapeutics, transforming the treatment landscape for chronic diseases such as cancer, autoimmune disorders, diabetes, and inflammatory diseases. However, the high cost of biologics has created substantial barriers to healthcare accessibility worldwide. Biosimilars—biological medicinal products that are highly similar to…

Author: Devanssh MehtaB.Pharm., M.Pharm. (Pharmacology), MBAMeerut, Uttar Pradesh, India Abstract Alkaloids represent one of the most pharmacologically significant classes of naturally occurring secondary metabolites. These nitrogen-containing organic compounds are primarily derived from plants but are also produced by microorganisms and marine organisms. Historically, alkaloids have served as the foundation of modern pharmacotherapy, providing numerous clinically important drugs including morphine, quinine,…

Devanssh MehtaM.Pharm (Pharmacology), MBA, B.PharmPharmacologist | Author | ResearcherMeerut, Uttar Pradesh, India Abstract Ficus racemosa Linn., a member of the Moraceae family, is a widely distributed medicinal plant extensively used in traditional systems of medicine such as Ayurveda, Siddha, and Unani. The plant, commonly known as the cluster fig or gular tree, has been traditionally employed for the treatment of…

Author: Devanssh MehtaM.Pharm (Pharmacology), MBA, B.PharmPharmacologist | Author | ResearcherMeerut, Uttar Pradesh, India Abstract Bauhinia racemosa, commonly known as the Bidi leaf tree, is a medicinal plant widely distributed across tropical and subtropical regions of Asia, particularly in India. The plant belongs to the family Fabaceae and has been traditionally used in Ayurvedic and folk medicine for the treatment of…

Author: Devanssh MehtaM.Pharm (Pharmacology), MBA, B.PharmPharmacologist | Author | ResearcherMeerut, Uttar Pradesh, India Abstract Benzene is a fundamental aromatic hydrocarbon widely used in industrial chemistry and serves as an important precursor for numerous chemical compounds including pharmaceuticals, plastics, dyes, and synthetic materials. Despite its industrial significance, benzene is recognized as a highly toxic and carcinogenic compound with profound effects on…

Author: Devanssh MehtaM.Pharm (Pharmacology), MBA, B.PharmPharmacologist | Author | ResearcherMeerut, Uttar Pradesh, India Abstract Alkanes are a class of saturated hydrocarbons characterized by single carbon–carbon bonds and the general molecular formula CₙH₂ₙ₊₂. These compounds are widely distributed in nature and are commonly found in petroleum, natural gas, and various industrial products. Although alkanes are primarily recognized for their importance in…

Author: Devanssh MehtaM.Pharm (Pharmacology), MBA, B.PharmPharmacologist | Author | ResearcherMeerut, Uttar Pradesh, India Abstract Cervical cancer remains one of the most significant malignancies affecting women worldwide, particularly in developing countries where access to screening and preventive healthcare services is limited. The disease arises primarily from persistent infection with high-risk types of human papillomavirus (HPV), which leads to genetic and molecular…

Author: Devanssh MehtaM.Pharm (Pharmacology), MBA, B.PharmPharmacologist | Author | ResearcherMeerut, Uttar Pradesh, India Abstract Cephalosporins represent one of the most widely used classes of β-lactam antibiotics in modern clinical medicine. Originally derived from the fungus Cephalosporium acremonium, these antimicrobial agents have undergone extensive chemical modification over the past several decades, resulting in the development of multiple generations of cephalosporins with…

Author: Devanssh MehtaM.Pharm (Pharmacology), MBA, B.PharmPharmacologist | Author | ResearcherMeerut, Uttar Pradesh, India Abstract Pharmacological animal models play a critical role in the advancement of biomedical research and drug discovery. These experimental systems are designed to replicate human physiological and pathological conditions in laboratory animals, enabling researchers to investigate disease mechanisms, evaluate pharmacological effects of new compounds, and assess the…

Author: Devanssh MehtaM.Pharm (Pharmacology), MBA, B.PharmPharmacologist | Author | ResearcherMeerut, Uttar Pradesh, India Abstract Sesquiterpenes represent an important class of naturally occurring terpenoid compounds widely distributed in essential oils, medicinal plants, and various botanical sources. Structurally characterized by a fifteen-carbon backbone derived from three isoprene units, sesquiterpenes exhibit remarkable chemical diversity and biological activity. Over the past few decades, these…

Author: Devanssh MehtaM.Pharm (Pharmacology), MBA, B.PharmPharmacologist | Author | ResearcherMeerut, Uttar Pradesh, India Abstract (≈250 words) Flavonoids constitute one of the most diverse groups of naturally occurring polyphenolic compounds widely distributed in fruits, vegetables, medicinal plants, and plant-derived beverages. Over the past few decades, flavonoids have attracted significant scientific interest due to their broad spectrum of pharmacological activities and potential…

Author: Devanssh MehtaM.Pharm (Pharmacology), MBA, B.PharmPharmacologist | Author | ResearcherMeerut, Uttar Pradesh, India Abstract Tobacco remains one of the most widely consumed psychoactive substances in the world and represents a major global public health concern. The pharmacological effects of tobacco are primarily mediated by nicotine, a potent alkaloid that acts on the central and peripheral nervous systems. Nicotine exerts its…

Author: Devanssh MehtaM.Pharm (Pharmacology), MBA, B.PharmPharmacologist | Author | ResearcherMeerut, Uttar Pradesh, India Abstract Serratiopeptidase, also known as serrapeptase, is a proteolytic enzyme widely recognized for its anti-inflammatory, fibrinolytic, and analgesic properties. Originally isolated from the non-pathogenic bacterium Serratia marcescens found in the digestive tract of silkworms, serratiopeptidase has gained considerable attention in modern pharmacology for its ability to reduce…

Author: Devanssh MehtaM.Pharm (Pharmacology), MBA, B.PharmPharmacologist | Author | ResearcherMeerut, Uttar Pradesh, India Abstract Paracetamol, also known as acetaminophen, is one of the most widely used analgesic and antipyretic medications worldwide. Despite its long history of clinical use and widespread availability as an over-the-counter drug, the pharmacological mechanisms underlying its therapeutic effects remain complex and continue to be explored. Unlike…